What will you be empowered to do?

Therapeutics

Scientist I, Computational Biology - Target Biology

South San Francisco, California, United States

Who We Are

Since 2006, 23andMe’s mission has been to help people access, understand, and benefit from the human genome. We are a group of passionate individuals pushing the boundaries of what’s possible to help turn genetic insight into better health and personal understanding.

Our Therapeutics team, established in April 2015, has been actively identifying novel drug targets from 23andMe’s unparalleled database and developing creative genomics-based strategies for prosecuting these targets. The Computational Biology group plays a key role from the initial target hypotheses through validation as well as translation to clinical development, ultimately participating in all phases of the therapeutic discovery and development processes.

Join our collaborative, cross-functional research team focused on discovery of novel therapeutic targets and their development in our laboratories!

 

Who You Are

The biological interpretation of genetic signals available to 23andMe requires computational methods to analyze high-throughput functional data, development of tools and reports that integrate genetics and functional genomics to drive target discovery, and summarizing the results in ways that enable efficient decision making.

We are looking for a quantitative scientist with extensive experience in computational biology. Ideal candidates will have demonstrated experience conducting creative and independent research analyzing a broad range of public or internally generated genomic datasets, with an emphasis on understanding the underlying biology.

In this role, you will extend existing target discovery efforts to incorporate additional data types and novel analysis methods; work toward identifying clinically relevant disease subtypes and associated therapeutic targets; and contribute to on-going therapeutic development programs. Our team is very collaborative, and the ability to communicate ideas and results to other scientists from different disciplines is key. 

 

What You’ll Bring

  • Ph.D. in Computational Biology, Bioinformatics, Biostatistics, Genetics or a related field
  • Knowledge of biology in at least one disease-relevant area (e.g., cardiovascular diseases, oncology, immunology, etc.)
  • Hands-on experience in the analysis of bulk RNA-seq, scRNA-seq or microarrays, and other large scale omics datasets
  • Fluency with tools and methods for processing functional sequencing data (RNA-seq, ATAC-seq, ChIP-seq or similar)
  • Strong quantitative skills and a background in statistical data analysis or machine learning
  • Experience in writing robust code in R or Python
  • Strong communication skills, with an ability to convey complex computational results to colleagues from a wide range of life sciences backgrounds
  • Ability to work in a dynamic team oriented environment

 

Pluses

  • Industry experience in pharmaceuticals or biotechnology
  • Expertise in genetics and the interpretation and fine mapping of genetic association signals
  • Extensive experience in writing robust code in a shared development environment

 

About Us

23andMe, headquartered in Sunnyvale, CA, is a leading consumer genetics and research company. Founded in 2006, the company’s mission is to help people access, understand, and benefit from the human genome. 23andMe has pioneered direct access to genetic information as the only company with multiple FDA authorizations for genetic health risk reports. The company has created the world’s largest crowdsourced platform for genetic research, with 80 percent of its customers electing to participate. The platform also powers the 23andMe Therapeutics group, currently pursuing drug discovery programs rooted in human genetics across a spectrum of disease areas, including oncology, respiratory, and cardiovascular diseases, in addition to other therapeutic areas. More information is available at www.23andMe.com.

At 23andMe, we value a diverse, inclusive workforce and we provide equal employment opportunity for all applicants and employees. All qualified applicants for employment will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws.  If you are unable to submit your application because of incompatible assistive technology or a disability, please contact us at accommodations-ext@23andme.com. 23andMe will reasonably accommodate qualified individuals with disabilities to the extent required by applicable law.

Please note: 23andMe does not accept agency resumes and we are not responsible for any fees related to unsolicited resumes. Thank you.

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