Let’s talk about Health Predispositions

Learn how genetics can impact the chances of developing certain health conditions. These topic pages include information on conditions highlighted in 23andMe Genetic Health Risk reports (which meet FDA requirements) and reports powered by 23andMe research.

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Genetics and Your Health

Discover how your genetics may influence your chances of developing certain diseases with the 23andMe Health Predisposition Reports, which include both reports that meet FDA requirements for Genetic Health Risks and reports powered by 23andMe research.* Our reports can reveal whether your genetic results are associated with a higher chance of developing certain health conditions. Keep in mind that these reports do not include all possible genetic variants that could affect these conditions. Other factors can also impact your chances of developing these conditions, including lifestyle, environment, and family history.

Discover what your unique genetics say about your chances of developing certain health conditions. These insights can help you make informed decisions about your health.

*23andMe health predisposition reports include both reports that meet FDA requirements for genetic health risks and reports which are based on 23andMe research and have not been reviewed by the FDA. The test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks. It is not intended to diagnose any disease. Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. The test is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatment. For certain conditions, we provide a single report that includes information on both carrier status and genetic health risk. Warnings & Limitations: The 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of the 185delAG and 5382insC variants in the BRCA1 gene and the 6174delT variant in the BRCA2 gene. The report describes if a woman is at increased risk of developing breast and ovarian cancer, and if a man is at increased risk of developing breast cancer or may be at increased risk of developing prostate cancer. The three variants included in this report are most common in people of Ashkenazi Jewish descent and do not represent the majority of BRCA1/BRCA2 variants in the general population. This report does not include variants in other genes linked to hereditary cancers and the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed in a clinical setting before taking any medical action. For important information and limitations regarding each genetic health risk report, visit 23andme.com/test-info/.