23andMeplus Total HealthTM.
Personalized care to empower preventive actions.

$999 First

Membership renews at $499peryr.


23andMeplus Total HealthTM.
Personalized care to empower preventive actions.

$999 First

Membership renews at $499peryr.

Clinician-ordered advanced genetic screening, biannual blood testing, and access to clinical services for early detection of potential disease.ΔLearn about Important Information for Total health

  • Identify disease risks with next-generation sequencing.
  • Biannual blood testing with advanced cardiometabolic biomarkers.
  • Meet with clinicians trained in genetics-informed care to receive a personalized health plan tailored to you.
  • Includes 23andMeplus PremiumTM
  • Valid payment method required at kit registration.

Not available to residents of HI, NJ, NY, OK, RI and US territories. Not currently available to existing 23andMe customers. Sign up to be the first to know when it’s available.

Our genotyping product detects 250 health-related variants in our Carrier Status and Genetic Health Risk reports. The Exome Sequencing reports detect 50,000+ hereditary disease-causing variants.

23andMeplus Total Health members get
the most advanced and comprehensive insights
and recommendations we offer.

Get all that 23andMeplus PremiumTM offers

190+ genotyping reports on your ancestry, health, wellness, traits and more.
Important test info.

Total Health
  • Exome

    Interpretations of 100+ genes linked to 55+ conditions

  • Biannual
    Blood Testing

    Analysis of 55+
    blood biomarkers

  • Genetics-informed
    Clinical Care

    Virtual clinical consultation
    and unlimited messaging

23andMe plus Total Health
Add to cart
$999 First
Membership renews at $499peryr.
Add to cart-totalHealth

Which service will you
start with today?

Remember, you can always upgrade without having to spit again.

FeatureAncestry ServiceHealth plus Ancestry Service


Add to cart-ancestry

Health plus Ancestry

Add to cart-healthImportant test info
Genotyping reports
Exome Sequencing ReportsΔLearn about Important Information for Total health
not includednot included
Ancestry and Trait Reportsincludedincluded
DNA Relative Finder and Family Tree (Opt in)includedincluded
Health Predisposition reports*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health Risks
not included10+
Carrier Status reports*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health Risks
not includedincluded
Wellness reports
not included5+
Family Health History Tree
not includedincluded
Pharmacogenetics reports**Learn about Considerations and Limitations for Pharmacogenetics Reports
not includednot included
Enhanced ancestry features
not includednot included
Just Added

Historical MatchesSM
not includednot included
Just Added

Breast, Prostate and Colorectal Cancer reports

all Powered by 23andMe Research
not includednot included
Health TracksSM
not includednot included
Health Action Plan
not includednot included
Ongoing new reports
and features
not includednot included
Blood TestingΔLearn about Important Information for Total health
not includednot included
Genetics-informed clinical careΔLearn about Important Information for Total health
not includednot included

Frequently Asked Questions

To be eligible for 23andMeplus Total Health, you must be 18 years or older and live in the US - excluding HI, NJ, NY, OK, RI and US territories (due to state and regional restrictions). You must not have received a blood transfusion in the last 30 days or a bone marrow transplant.

Currently, Total Health is only available to new, non-genotyped customers. If you're a current customer, we're still in the process of building an upgrade path for you to upgrade within your current account. We want to ensure all the foundations are in place for you to have an optimal experience with the service at a special upgrade price.

Because there are multiple steps involved with 23andMeplus Total Health, your reports will arrive over a period of time after you complete certain steps. The estimated timeline is as follows:

  • You'll receive 190+ genotyping reports 4-6 weeks after registering your kit, spitting and shipping your sample.
  • You'll receive your exome sequencing reports 7-12 weeks after you receive your genotyping reports.
  • For each of the two blood tests, you'll receive your analysis of 55+ biomarkers 3-5 business days after completing your blood draw.
  • You'll have unlimited messaging with clinicians after receiving your PGS results and the opportunity to schedule your virtual consultation once exome results are returned.

All saliva samples are processed in Clinical Laboratory Improvement Amendments (CLIA) certified and College of American Pathologists (CAP) accredited labs.

Clinical services are provided by healthcare providers which includes board-certified physicians and nurse practitioners. All clinicians have unique knowledge and training in genetics-informed care.

Genotyping examines DNA variants at certain pre-identified positions in the genome. The specific variants we look at provide coverage of common known variations across the entire genome. Many variants can be accurately and efficiently examined at once using genotyping chips, also known as microarrays. This is the technology used to power the 190+ genotyping reports that you will receive.

Sequencing is an advanced type of genetic testing which involves determining the exact sequence of a certain length of DNA - a short piece, the whole genome, or parts of the genome such as the exome. It can be used to examine known variants, as well as identify variants that are unknown, providing you with a more complete picture of your genetic predispositions for certain health conditions. Exome sequencing looks at approximately40 times more DNA bases than microarray genotyping chips.

Exome sequencing is a specialized genetic sequencing technique that focuses on decoding the exome of an individual's genome. The exome represents the protein-coding regions of genes, which make up only about 1-2% of the entire genome but contain the majority of genetic variants associated with disease risk. By selectively sequencing these regions, exome sequencing provides valuable insights into an individual's genetic makeup, identifying variations that may be linked to specific genetic disorders or conditions. This technique is particularly useful for diagnosing rare genetic diseases and conducting research into the genetic basis of various medical conditions.

The 100+ genes included in the 23andMeplus Total Health Exome Sequencing reports were carefully selected to provide high-impact genetic risk information for 55+ conditions. These include all of the genes considered “medically actionable” by the American College of Medical Genetics and Genomics (ACMG) along with other genes that can provide both clinical and personal benefit. Overall, the genes selected can inform you about conditions that are often underdiagnosed. But, if detected early, there are many effective preventive measures and clinical interventions. See a full list of the genes and conditions .

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