23andMe Genetic Health Risk Reports:
What you should know
We encourage you to speak to a genetic counselor
There are many things to think about when deciding whether genetic testing is right for you. Although these tests can provide important information about health risks, they can also be upsetting or raise questions about what the results mean. Genetic tests also have certain limitations that are important to understand. Your personal and family medical history, as well as your goals for testing, should all factor into your decisions about whether and how to test.
A genetic counselor, a healthcare professional with special training in genetic conditions, will be able to answer your questions and help you make an informed choice. We recommend that you speak with a genetic counselor before testing, and also after testing to help you understand your results and what actions you should take. This is especially important for health conditions that are preventable or treatable.
sample questions to discuss with a genetic counselor:
Variant(s) not detectedYou do not have the variant(s) we tested. Since these tests do not include all variants that may impact your risk of developing a condition, you may still have another variant that could affect your risk. Non-genetic factors may also affect your risk.
Variant(s) detectedYou have one or more of the variants we tested. You may be at increased risk for the condition based on this result. This does not mean you will definitely develop the condition. Other factors may also affect your risk.
Result not determinedYour test result could not be determined. This can be caused by random test error or other factors that interfere with the test.
In some cases, the laboratory may not be able to process your sample. If this happens, we will notify you by email and you may request one free replacement kit.
Other companies offering genetic risk tests may include different variants for the same health condition. This means that it's possible to get different results using a test from a different company.
If your report says you have variants associated with increased risk
- Consider sharing the result with a healthcare professional.
- Certain results, such as having a variant detected for the BRCA1/ BRCA2 (Selected Variants) report, may warrant prompt follow-up with a healthcare professional, since effective options may exist to prevent or reduce risk for disease. Each report will provide more specific guidance.
- Consider sharing your results with relatives. They may also have these variants. Keep in mind that some people may not want to know information about genetic health risks.
If your report says you do not have any risk variants detected
- Continue to follow screening and other healthy behaviors recommended by your healthcare provider. This is because our reports do not cover all factors that might influence risk.
Concerned about your risk?
- If you have other risk factors for the condition, you should discuss the condition with a doctor.
- You can also discuss your results with your healthcare provider or a genetic counselor.
Genetic Health Risk reports are intended to provide you with genetic information to inform conversations with a healthcare professional. These reports should not be used to make medical decisions. Always consult with a healthcare professional before taking any medical action.
You will be asked whether you want to receive certain Genetic Health Risk reports
Some of our reports are about serious diseases that may not have an effective treatment or cure. Some people may be upset by learning about personal risks, and risks for family members who share DNA. 23andMe will not share your personal information with an insurance company without your explicit consent. Learn more about third party information sharing here.
You can choose to exclude the following reports individually from your account before your results are returned to you:
- BRCA1/BRCA2 (Selected Variants)
- Hereditary Prostate Cancer (HOXB13-Related)
- Late-Onset Alzheimer’s Disease
- MUTYH-Associated Polyposis
- Parkinson’s Disease
If you are interested in receiving these reports, we recommend that you consult with a genetic counselor before purchasing. Additional relevant information about these reports will be provided when you go through the process of setting your report preferences, after registering your kit.